Occurrence of changes in the auditory evoked potentials of smokers: systematic review of the literature

ABSTRACT Purpose To verify the occurrence of abnormal auditory evoked potentials (AEP) tests in adult smokers. Research strategies Systematic review literature according to PRISMA guidelines, answer question: “Are there any changes AEP results smokers?”, PECOS strategy. carried out on PubMed, Embase, CINAHL, LIVIVO, Scopus, Web Science, LILACS and Scielo databases. Additional search gray literature: Google Scholar ProQuest hand searching reference lists included studies. Selection criteria Cross-sectional studies were selected, without restriction year publication language. Data analysis First, titles abstracts all analyzed, followed by full reading eligible Results 898 articles collected, after duplicate removed blind three researchers, 8 observational type selected. Most have found an association between active smoking electrophysiological tests. Conclusion Normal hearing smokers present alterations short long AEP. In brainstem response, main altered components increase waves latencies I III interpeaks - V, as well a decrease amplitude waves. Mismatch Negativity, was significant wave latency. latency potential, P300, decreased amplitudes N1 (in Fz) P3.